Multimodal creativity assessments following acute and sustained microdosing of lysergic acid diethylamide

2
  • The LSD microdosing regimen (10µg, x14) did not show any statistically significant impact on creativity as measured through established tests.
  • Participants reported subjective feelings of increased creativity during microdosing days but these perceptions did not align with objective assessments.
  • Several factors, including laboratory conditions, limitations in creativity testing, and potential placebo effects, may explain the discrepancy between self-reported creativity and measured outcomes.

Studying Microdosing and Creativity

The present research investigates the debated notion that microdosing, defined as the administration of very low doses of psychedelics, could enhance creativity. Despite numerous anecdotal accounts claiming benefits, previous empirical studies exhibited mixed or inconclusive results, prompting the authors to reassess this claim scientifically. By utilizing various creativity assessments, they aimed to clarify whether microdosing has a verifiable impact on creativity levels.

Challenges in Assessing Creativity

The article discusses the complexities involved in defining creativity, emphasizing the lack of consensus over its definition and challenges inherent in developing effective measurement tools. Creativity is traditionally viewed as the ability to generate unique ideas that hold practical value. However, the balance between novelty and utility is context-dependent, which complicates the evaluation process.

Psychedelics and Creative Thought

Understanding the potential link between psychedelics and creativity, the article proposes a framework known as the Dynamic Frameworks of Thought (DFT). This model categorizes different mental states based on levels of constraint imposed on thinking processes. Creative engagement involves oscillating between periods of unrestrained ideation and focused evaluation. Psychedelic experiences, particularly at higher doses, might relax these constraints, allowing for more inventive thought patterns. However, this unstructured thinking may detract from evaluating the practicality of arising ideas.

Investigating Microdosing: The MDLSD Trial

The MDLSD trial sought to provide clarity in the relationship between microdosing and creativity. In this placebo-controlled study involving 80 healthy male participants, subjects were assigned to receive either a microdose of LSD or placebo over six weeks, with creativity evaluated at several key intervals. This meticulous design aimed to reveal both short-term and long-lasting impacts on creativity resulting from the microdosing regimen.

Creativity Measures Employed in the Study

To accurately assess creativity, the researchers implemented a variety of tasks: the Alternate Uses Test (AUT) measured divergent thinking, while the Remote Associates Task (RAT) focused on convergent thinking. The Consensual Assessment Technique (CAT) involved creating an artistic piece, rated for creativity and quality by expert judges, and the Everyday Problem-Solving Questionnaire (EPSQ) sought to evaluate individuals’ self-assessed problem-solving skills in real-life situations. By diversifying assessment methods, the researchers aimed to capture a full spectrum of creative processes.

Results: No Significant Effects Observed

The findings from the MDLSD trial revealed no statistically significant improvements in creativity measures attributable to LSD microdosing. The assessments from the AUT, RAT, CAT, and EPSQ consistently failed to distinguish differences between the microdose and placebo participants. Interestingly, a notable effect was found relating participants’ vocabulary skills to their performance on creativity tasks, emphasizing the importance of linguistic competence in such evaluations.

Exploring Possible Explanations for Discrepancies

Despite the lack of objective evidence supporting creativity enhancements from microdosing, the trial participants reported a subjective increase in creativity. This raises questions about the underlying mechanisms influencing these perceptions. The authors propose several explanations, including the pressures of a laboratory setting that may stifle creative expression, the insensitivity of traditional creativity tests to nuanced changes, and the likelihood of placebo effects driving perceived improvements. Additionally, the dichotomy between subjective sensations of creativity versus measurable performance casts further uncertainty on the role of microdosing. See also our coverage of Microdosing psychedelics and its effect on creativity, and our explainers on microdosing protocol. Read the full paper summary on Blossom.

JOIN OUR COMMUNITY!

 Want to stay updated about microdosing research, the latest news, tips & tricks, and more? Subscribe to our newsletter below and stay in the loop about everything microdosing!