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Participate in Research: The effects of San Pedro (Mescaline) Microdosing

Microdosing San Pedro

Microdosing Institute is proud to present another research project that is now taking place at the Neuropsychology and Psychopharmacology department of Maastricht University. You can still sign up to be a participant in this online study.

What’s being studied? The effects of the teacher plant (cactus) San Pedro on mental wellbeing and memory, when taken in microdosing quantities.

For this study, we seek males and females who intend to start microdosing with mescaline on own initiative, in other words the UVM does not provide substances for this study.

san pedro slice

How does this online study work?

This Microdosing San Pedro study is conducted online. Before the start of your microdosing routine we want you to fill in some questionnaires about your wellbeing, and perform a computerized memory task on your laptop or computer. On the days you microdose, you are asked to keep track of your experience in an online diary with questionnaires using an app on your phone. At the end of a 4 week period of microdosing (or when you decide to stop), we ask you to fill in some questionnaires and perform the memory task again. You will not receive any remuneration or reward for participation.

We are not encouraging people to microdose. Participants will have to take part based on their own initiative and they will have to use their own substance. Our intention is to observe people who already use psychedelics and to allow them to make their self-experimentation scientifically more meaningful by participating in this San Pedro Study.

Purpose of the Study

The present study explores the effects of microdosing with San Pedro (mescaline) on mental wellbeing and memory. Several internet fora discuss positive effects on mental wellbeing and increased focus when microdosing with this substance. However, these reports are subjective, scientific data containing measurements on these effects of microdosing with mescaline is lacking to date. We, therefore, want to capture these effects with measurements that are used in the scientific field. The information we gather with this study can be of value in order to start placebo-controlled experimental studies to further explore the effects.

Selection participation
Participants need to have had previous experience with a psychedelic prior to participation of this study. We have chosen to include participants who intend to start microdosing with mescaline on their own initiative. Your participation is completely voluntary and you have the right to decline and withdraw your consent and leave the study at any time without having to give a reason.

Your participation will last no longer than 4 weeks (depending on your own microdosing schedule). Because we would like to test the effect of microdosing with mescaline on your well-being and functioning, we will make one measurement prior to the start of microdosing and one measurement after 4 weeks of microdosing (or when you stopped microdosing) via an online link. Furthermore, we also ask you to keep track of a diary on the days you microdose via an app.


We want to ask you to reflect on your participation in this scientific study BEFORE you start microdosing with mescaline. If you decide to participate, you can continue to the informed consent form.

Pre- and post- measurement

Both PRIOR to microdosing and AFTER 4 weeks of microdosing we ask you to fill in some questionnaires and perform a short working memory task on your laptop or computer.

Requirements of the study
The Microdosing San Pedro study will be in English
There is no age limit for participation
You will need a computer or Smartphone for installing the tracking app you will be using.
You need to have experience with psychedelics
You will need to obtain your substance yourself.
Want to Participate?
In case you would like to participate and start right away, please click this link below :

For more information about the study and how to use the tracking app, you can send an email: fpn-epuonderzoek120@maastrichtuniversity.nl

Tracking App mEMA
For this study you can choose between using a tracking app, which you have to install on your phone, or simply by filling in a questionary on your computer.

Download the tracking app for Android here.

Download the tracking app for Apple (IOS) here.

Microdosing San Pedro Cactus? How do I get started?

Learn how to prepare San Pedro Cactus for microdosing on this page.

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6 thoughts on “Participate in Research: The effects of San Pedro (Mescaline) Microdosing”

  1. I started MD a few months ago and I absolutely find it to be the best solution for many reasons. I’m ready to continue my education as well as meet some cool people.

  2. I’ve been microdosing San Pedro for over two years on and off as well as facilitating the medicine for others. I’d love this opportunity and to be able to hep with these studies based off of my extensive research of this powerful heart medicine !

  3. Hello, I am starting my first microdosing experiment next week with truffles. After that I would most certainly want to participate in the UM studies. lots of microlove. Anna

  4. I am 70 yrs old, having suffered Depression, low Self~Esteem for decades and long~term Psychiatric Medication gives me severe side~effects. I welcome this opportunity to enter Research into Plant based remedies, in the hope that I can end my days more Mentally, Emotionally and Spiritually in tune with Mother Earth.

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