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Can Microdosing Be Combined With Medication or Supplements?

Many people wonder if microdosing can be combined with medication. This is one of the most frequently asked questions for researchers and experts in this field. To effectively answer that question, Dr. James Fadiman and his colleague Sophia Korb compiled a list of medications, supplements, and drugs until now are known not to cause any adverse side effects when combined with microdosing. 

The list stems from the data collected through their long-term study from hundreds of subjects who have microdosed independently with (mainly) LSD1P-LSD, or psilocybinWe want to emphasize that this list does not guarantee that you can use microdose safely and responsibly while taking any of the medications listed. Read more about the risks of microdosing.

It is important to:

  • Always consult your doctor first if you plan to combine, stop, or phase out medications
  • Remember: no one is currently knowledgeable enough in the field of microdosing to be able to advise you on the interactions of microdosing and your medications. If you want to taper off medications because you suspect that microdosing is a better alternative, always consult with your doctor and thoroughly research the pros and cons!

Have you experienced problems with microdosing in combination with your medication? Or do you have an addition to the list? Please get in touch with us!

TIP: To search for a specific substance use, CTRL + F (or CMD + F on Mac)

Painkillers

    • Acetomenophen/paracetemol (Tylenol)
    • Aspirin
    • Codeine
    • Dihydrocodeine (Co-dydramol)
    • Hydrocodone (Vicodin, Norco)
    • Ibuprofen (Advil, Motrin)
    • Naproxen (Aleve)
    • Tramadol (Ultram)

– Do not microdose while taking Tramadol

Heart/high blood pressure medication

  • amiodarone (Cordarone, Nexterone)
  • hydrochlorothiazide (HCTZ, HCT)
  • lisinopril (Prinivil, Zestril)
  • losartan (Cozaar)
  • spironolactone (Aldactone)
  • telemisartin (Micardis, Actavis)
  • valsartan (Diovan)

Birth-control

  • Aubra
  • Hormonal pills
  • Marvelon
  • Mirena
  • Nuvaring
  • Tricyclen

Antacid

  • Ranitidine (Zantac)

Antibiotics

  • clindamycin (Cleocin, Dalacin, Clinacin)
  • Doxycycline
  • Minocycline (Minocin, Minomycin, Akamine)
  • Penicillin (Bicillin)

Antifungals

  • Fluconazole (Diflucan, Celozole)

Focus medication (ADHD/ADD)

  • Amphetamine (Adderall)
  • Bupropion (Wellbutrin)
  • Dextroamphetamine (Dexedrine, Metamina, Attentin, Zenzedi, Procentra, Amfexa)
  • Lisdexamfetamine (Vyvanse)
  • Methylphenidate (Ritalin, Biphentin)
  • Modafinil (Provigil)

Sleeping

  • Zopiclone (Zimovane, Imovane)
  • Melatonin
  • Zolpidem (ambien, stilnox)

Antihistamines

  • Cetirizine (Zyrtec)
  • Diphenahydramine (Benadryl, Gravol)
  • Loratadine (Claritin)
  • Ranitidine (Zantac)

Benzodiazepines (anxiety, sleep, seizure)

  • Alprazolam (Xanax)
  • Clonazepam (Klonopin)
  • Diazepam (Valium)
  • Flurazepam (Staurodorm)
  • Lorazepam (Ativan)

Other anxiolytic

  • Etizolam
  • Propranolol

Parkinson’s medication

  • Levodopa
  • Pramipexole

Cholesterol medication

  • Atorvastatin (Lipitor)
  • Rosuvastatin (Crestor)
    Simvastatin (Zocor)
  • Statins

Racetams

  • Aniracetam
  • Phenylpiracetam
  • Piracetam

Mood stabilizers and antipsychotics

  • Aripiprazole (Abilify)
  • Buspirone (Buspar)
  • Lamotrigine (Lamictal)
  • Lithium

  • Quetiapine (Seroquel)

– Do not microdose while taking Lithium

Diabetes

  • Metformin (Glucophage)

Anticonvulsants

  • Baclofen (Lioresal)
  • Carbamazepine (Tegretol)
  • Cyclobenzaprine (Flexeril)
  • Gabapentin
  • Mirtazapine
  • Sodium valproate
  • Tizanidine (Zanaflex)

Thyroid medication

  • Methimazole or thiamazole

Antidepressants

  • Bupropion (Wellbutrin)
  • Citalopram (Celexa)
  • Desvenlafaxine (Pristiq)
  • Doxepin (Sinequan)
  • Duloxetine (Cymbalta)
  • Escitalopram (Lexapro)
  • Paroxetine (Paxil)
  • Sertraline (Zoloft)
  • Venlafaxine (Effexor)

GERD

  • Esomeprazole (Nexium)
  • Pantoprazole (Protonix)
  • Ranitidine (Zantac)

Breathing (asthma, COPD)

  • Salbutamol (Albuterol)
  • Cetirizine (Zyrtec)
  • Beclometasone (Clenil Modulite)
  • Montelukast (Singulair)

Antiviral

  • Nitazoxanide

Recreational drugs

  • Alcohol
  • Amphetamine (speed)
  • Heroin
  • Kratom
  • Marijuana (cannabis)
  • Nicotine

Anti-inflammatory

  • Mesalazine (Octasa)

Immunosuppressant

  • Hydroxychloroquine (Quensyl)

Erectile Dysfunction

  • Tadalafil (Cialis)

Alcohol dependence treatment

  • Acamprosate (Campral)
  • Disulfiram (Antabuse)
  • Naltrexone

Hormones and Steroids

  • Norethindrone Acetate ethinyl
  • Estradiol
  • Prednisone (Deltasone, Liquid Pred, Orasone, Adasone, Deltacortisone)
  • Estrogen (Premarin)
  • Progesterone (Prometrium, Utrogestan, Endometrin)
  • Testosterone
  • Levothyroxine (Synthroid)
  • Naturethroid
  • Dexamethasone

DHEA

  • spironolactone (Aldactone)

Supplements

  • 5-HTP
  • Albizia
  • Ashwagandha
  • B100
  • BCAAs
  • Biotin
  • Brahmi
  • Bromelain
  • Caffeine
  • Calcium
  • Cayenne
  • Chaga
  • Chlorophyll
  • Choline
  • CILTEP
  • CoQ10
  • Cordyceps
  • Creatine
  • Eleuthero
  • EPA/DHA
  • Fish oil
  • Ginseng
  • Glucosamine
  • Iodine
  • Iron
  • Kelp
  • Kratom
  • L-theanine
  • Lemon balm
  • Lion’s Mane
  • Maca
  • Magnesium
  • MCT
  • Methyl sulfonyl methane (MSM)
  • Milk thistle
  • Multivitamins
  • Mmega 3/6/9
  • Passionflower
  • Phosphatidyl
  • Probiotics
  • Pycnogenol
  • Reishi
  • Rhodiola
  • Rosacea
  • Selenium
  • Shatavari
  • Skullcap
  • Johns wort
  • Taurine
  • Tulsi
  • Turmeric (curcumin)
  • Turkey’s tail
  • Twynsta
  • Vitamin
    • B6
    • B12
    • D3
    • K
    • C
    • K2
    • D
  • Zinc
  • Zinium

Disclaimer

The content on this website and the other Microdosing Institute channels is for informational and educational purposes only, and does not substitute professional medical advice or consultation with healthcare professionals. If you are seeking medical advice, diagnose, or treatment, we advise you to consult a medical professional or healthcare provider. Equally, we cannot help with the sourcing of illegal substances.